《Evaluation of composition effects on the physicochemical and biological properties of polypeptide-based hydrogels for potential application in wound healing》 was published in Polymers (Basel, Switzerland) in 2021. These research results belong to Giliomee, Johnel; du Toit, Lisa C.; Kumar, Pradeep; Klumperman, Bert; Choonara, Yahya E.. Recommanded Product: H-Lys(Boc)-OH The article mentions the following:
In this study, the effect of crosslinking and concentration on the properties of a new library of low-concentration poly(Lys60-ran-Ala40)-based hydrogels for potential application in wound healing was investigated in order to correlate the hydrogel composition with the desired physicochem. and biofunctional properties to expand the assortment of poly-L-lysine (PLL)-based hydrogels suitable for wound healing. Controlled ring-opening polymerization (ROP) and precise hydrogel compositions were used to customize the physicochem. and biofunctional properties of a library of new hydrogels comprising poly(L-lysine-ran-L-alanine) and four-arm poly(ethylene glycol) (P(KA)/4-PEG). The chem. composition and degree of crosslinking via free amine quantification were analyzed for the P(KA)/4-PEG hydrogels. In addition, the rheol. properties, pore morphol., swelling behavior and degradation time were characterized. Subsequently, in vitro cell studies for evaluation of the cytotoxicity and cell adhesion were performed. The 4 wt% 1:1 functional molar ratio hydrogel with P(KA) concentrations as low as 0.65 wt% demonstrated low cytotoxicity and desirable cell adhesion towards fibroblasts and thus displayed a desirable combination of properties for wound healing application. The experimental part of the paper was very detailed, including the reaction process of H-Lys(Boc)-OH(cas: 2418-95-3Recommanded Product: H-Lys(Boc)-OH)
H-Lys(Boc)-OH(cas: 2418-95-3) belongs to amino acids. Amino acids are not generally considered to be electrochemically active because products of the oxidation accumulate on the electrode surface and prevent it from participating in any further electrochemical processes.Recommanded Product: H-Lys(Boc)-OH
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Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics