《An easy and convenient synthesis of Weinreb amides and hydroxamates》 was written by de Luca, Lidia; Giacomelli, Giampaolo; Taddei, Maurizio. Synthetic Route of C13H26N2O4 And the article was included in Journal of Organic Chemistry on April 6 ,2001. The article conveys some information:
A simple and convenient one-flask method for the preparation of Weinreb amides, hydroxamates, and hydroxamic acids on a large scale used mild reaction conditions and inexpensive reagents; the methodol. is a useful addition to parallel syntheses. Thus, reacting PhCO2H with MeNHOMe in THF containing 2-chloro-4,6-dimethoxy-1,3,5-triazine [CMDT], 4-(4,6-dimethoxy-1,3,5-triazin-2-yl)-4-methylmorpholinium chloride [DMTMM], or cyanuric chloride and N-methylmorpholine [NMM] gave the amide PhCONMeOMe in high yields. The results came from multiple reactions, including the reaction of (S)-N-Methyl-N-methoxy-2-(tert-butoxycarbonylamino)-4-methylpentanamide(cas: 87694-50-6Synthetic Route of C13H26N2O4)
(S)-N-Methyl-N-methoxy-2-(tert-butoxycarbonylamino)-4-methylpentanamide(cas: 87694-50-6) belongs to amides.Synthetic Route of C13H26N2O4 Amides include many other important biological compounds, as well as many drugs like paracetamol, penicillin and LSD. Low-molecular-weight amides, such as dimethylformamide, are common solvents.
Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics