《Nickel-Catalyzed Cross-Coupling of Sulfonamides With (Hetero)aryl Chlorides》 was written by McGuire, Ryan T.; Simon, Connor M.; Yadav, Arun A.; Ferguson, Michael J.; Stradiotto, Mark. Product Details of 70-55-3 And the article was included in Angewandte Chemie, International Edition in 2020. The article conveys some information:
The development of Ni-catalyzed C-N cross-couplings of sulfonamides with (hetero)aryl chlorides is reported. These transformations, which were previously achievable only with Pd catalysis, are enabled using air-stable (L)NiCl(o-tol) pre-catalysts (L = PhPAd-DalPhos and PAd2-DalPhos), without photocatalysis. The collective scope of (pseudo)halide electrophiles (X = Cl, Br, I, OTs, and OC(O)NEt2) demonstrated herein is unprecedented for any reported catalyst system for sulfonamide C-N cross-coupling (Pd, Cu, Ni, or other). Preliminary competition experiments and relevant coordination chem. studies are also presented. In the experimental materials used by the author, we found 4-Methylbenzenesulfonamide(cas: 70-55-3Product Details of 70-55-3)
4-Methylbenzenesulfonamide(cas: 70-55-3) belongs to anime. Many important products require amines as part of their syntheses. Methylamine is utilized in the production of the analgesic meperidine (trade name Demerol) and the photographic developer Metol (trademark), and dimethylamine is used in the synthesis of the antihistamine diphenhydramine (trade name Benadryl), the solvent dimethylformamide (DMF), and the rocket propellant 1,1-dimethylhydrazine. The synthesis of the insect repellent N,N-diethyl-m-toluamide (DEET) incorporates diethylamine while that of the synthetic fibre Kevlar requires aromatic amines.Product Details of 70-55-3
Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics