Liu, Peng; Chen, Xiaozhong; Xu, Xiangchao; Yang, Linlin; Zeng, Guixiang; Ye, Chuang; Shi, Qixun; Yang, Jiazhi; Li, Feng published the artcile< From hydrogen autotransfer process to deuterium autotransfer process: The N-trideuteromethylation of amines with deuterated methanol to trideuteromethylated amines catalyzed by a Cp*Ir complex bearing a flexible bridging and functional ligand>, Category: amides-buliding-blocks, the main research area is perdeuteromethanol amine iridium catalyst trideuteromethylation green chem; trideuteromethylamine preparation; sulfonamide perdeuteromethanol iridium catalyst trideuteromethylation green chem; trideuterosulfonamide preparation.
A Cp*Ir complex bearing a flexible and functional 6,6′-(OH)2-2,2′-dipyridylamine ligand was designed, synthesized and found to be a general and efficient catalyst for the synthesis of trideuteromethylated amines via the N-trideuteromethylation of amines with deuterated methanol based on the proposed deuterium autotransfer process. The synthetic strategy was attractive due to easily available deuterium source, high atom efficiency and environmental friendliness. It was confirmed that OH units in the ligand were crucial for the catalytic activity. Furthermore, a metal-ligand cooperative mechanism was also proposed based on exptl. results and DFT calculations
Journal of Catalysis published new progress about Amines Role: RCT (Reactant), SPN (Synthetic Preparation), RACT (Reactant or Reagent), PREP (Preparation). 6961-82-6 belongs to class amides-buliding-blocks, and the molecular formula is C6H6ClNO2S, Category: amides-buliding-blocks.
Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics