Chen, Jun; Shi, Zhan; Lu, Ping published the artcile< Enantioselective Synthesis of Indanes with a Quaternary Stereocenter via Diastereoselective C(sp3)-H Functionalization>, Electric Literature of 1192620-83-9, the main research area is bromofluorodihydroindenol enantioselective preparation crystal structure; chiral bromobenzoyldihydroindene enantioselective preparation crystal structure; mol structure chiral bromobenzoyldihydroindene bromofluorodihydroindenol; indane enantioselective preparation; indanone preparation diastereoselective carbon hydrogen bond activation reaction.
A practical synthesis of enantioenriched indane derivatives with quaternary stereocenters was developed via sequential enantioselective reduction and C-H functionalization. Good to excellent enantioselectivity could be achieved by either the CuH-catalyzed asym. reduction or the Corey-Bakshi-Shibata (CBS) reduction of indanone derivatives The subsequent diastereospecific and regioselective Rh-catalyzed silylation of the Me C-H bond led to indane derivatives with quaternary centers. This strategy was further applied in syntheses of (nor)illudalane and botryane sesquiterpenoids.
Organic Letters published new progress about C-H bond activation. 1192620-83-9 belongs to class amides-buliding-blocks, and the molecular formula is C30H31ClN2O2RuS, Electric Literature of 1192620-83-9.
Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics