Tong, Jing; Xiang, Lulu; Niu, Yichao; Zhang, Ting published the artcile< Effect of orlistat intervention on in vitro fertilization/intracytoplasmic sperm injection outcome in overweight/obese infertile women>, Quality Control of 96829-58-2, the main research area is CRP fertilization overweight obese infertile; Orlistat; clinical pregnancy rate; in vitro fertilization/intracytoplasmic sperm injection; obese; overweight.
ObjectiveThis retrospective study sought to evaluate the effect of orlistat intervention on the outcome of in vitro fertilization/intracytoplasmic sperm injection (IVF/ICSI) in overweight/obese infertile women. MethodsTwenty-nine overweight/obese patients undergoing IVF/ICSI for the first time were treated with orlistat intervention (orlistat group). Another 29 patients with matched age and body mass index (BMI) were included in the control group at a ratio of 1:1. Clin. data of both groups were collected, and the clin. baseline data, IVF/ICSI cycle information and embryo transfer outcome were compared between groups by Students t-test or chi-square test when appropriate. ResultsThe 29 patients in the orlistat group completed 37 embryo transfer cycles, and the 29 subjects in the control group completed 38 embryo transfer cycles. There was no significant difference in the clin. baseline data or IVF/ICSI cycle data between the two groups (p > .05). In the end, 22 transfer cycles in orlistat group obtained clin. pregnancies, 5 obtained biochem. pregnancies and 10 had non-pregnancies. As for the control group, 15 transfer cycles obtained clin. pregnancies, 15 achieved biochem. pregnancies and 8 had non-pregnancies. The clin. pregnancy rate of the orlistat group was significantly higher than that of the control group (59.46% vs. 39.47%, p = .004), but there was no significant difference in the live birth rate between the two groups (54.05% vs. 36.84%, p > .05). ConclusionsOrlistat intervention for overweight/obese infertile women receiving IVF/ICSI treatment will increase the clin. pregnancy rate, without affecting the total amount of gonadotropins, ovarian stimulation time or the follicular output rate (FORT).
Gynecological Endocrinology published new progress about Adiponectins Role: BSU (Biological Study, Unclassified), BIOL (Biological Study). 96829-58-2 belongs to class amides-buliding-blocks, and the molecular formula is C29H53NO5, Quality Control of 96829-58-2.
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