The author of 《A Green and Sustainable Approach for Selective Halogenation of Anilides, Benzanilides, Sulphonamides and Heterocycles》 were Lakshmireddy, V. M.; Naga Veera, Y.; Reddy, T. J.; Rao, V. J.; China Raju, B.. And the article was published in Asian Journal of Organic Chemistry in 2019. COA of Formula: C9H7ClF3NO The author mentioned the following in the article:
An efficient green and sustainable protocol was devised for the selective oxidative halogenation of acetanilides, benzanilides, sulfonamides and heterocyclic compounds to afford haloanilides and halosulfonamides I [R = COMe, COPh, SO2Ph; R1 = Cl, Br; R2 = H, F; R3 = H, i-Pr, CF3, etc.; R4 = H, F, Br, etc.], haloimidazoles, haloindoles, halothiazoles and 1,2,4-triazole e.g. II and halopyridines III [R5 = NH2, NHCOMe, Br, etc.; R6 = NH2, Cl, Br, etc.; R7 = H, NH2, NH(Me)2, NHCOMe; R8 = H, Cl, Br] using easily available NaX as a halogen source and oxone as a powerful oxidant. The present protocol was simple and environmentally benign to conduct the laboratory scale halogenations and could be extended to prepare industrially important compounds In the experiment, the researchers used many compounds, for example, N-(2-Chloro-4-(trifluoromethyl)phenyl)acetamide(cas: 247170-19-0COA of Formula: C9H7ClF3NO)
N-(2-Chloro-4-(trifluoromethyl)phenyl)acetamide(cas: 247170-19-0) belongs to anime. Many important products require amines as part of their syntheses. Methylamine is utilized in the production of the analgesic meperidine (trade name Demerol) and the photographic developer Metol (trademark), and dimethylamine is used in the synthesis of the antihistamine diphenhydramine (trade name Benadryl), the solvent dimethylformamide (DMF), and the rocket propellant 1,1-dimethylhydrazine. The synthesis of the insect repellent N,N-diethyl-m-toluamide (DEET) incorporates diethylamine while that of the synthetic fibre Kevlar requires aromatic amines.COA of Formula: C9H7ClF3NO
Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics