Cheloufi, H’s team published research in Molecular Diversity in 2016-05-31 | 25999-04-6

Molecular Diversity published new progress about Antitumor agents. 25999-04-6 belongs to class amides-buliding-blocks, and the molecular formula is C4H10N2O3S, Product Details of C4H10N2O3S.

Cheloufi, H.; Belhani, B.; Ouk, T. S.; Zerrouki, R.; Aouf, N.-E.; Berredjem, M. published the artcile< Synthesis and antitumor evaluation of novel sulfonylcycloureas derived from nitrogen mustard>, Product Details of C4H10N2O3S, the main research area is sulfonylcyclourea derive nitrogen mustard; Antitumor; Cancer; Nitrogen mustard; Sulfonamides; Sulfonylcycloureas.

A new series of sulfonylcycloureas derivatives have been synthesized and evaluated in vitro for their antitumor activity against four cancer cell lines (A431, Jurkat, U266, and K562). These compounds were prepared by the condensation of several sulfonamides (2a-m) with Et bis(2-chloroethyl)carbamate (1a). The relative cytotoxicity of these new derivatives in comparison to chlorambucil is reported.

Molecular Diversity published new progress about Antitumor agents. 25999-04-6 belongs to class amides-buliding-blocks, and the molecular formula is C4H10N2O3S, Product Details of C4H10N2O3S.

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics