Vyas, Vijyesh K.; Bhanage, Bhalchandra M. published the artcile< Kinetic Resolution Driven Diastereo- and Enantioselective Synthesis of cis-β-Heteroaryl Amino Cycloalkanols by Ruthenium-Catalyzed Asymmetric Transfer Hydrogenation>, Reference of 1192620-83-9, the main research area is azolyl cycloalkanol diastereoselective enantioselective preparation; tethered ruthenium catalyst asym transfer hydrogenation azolyl ketone; dynamic kinetic resolution azolyl ketone tethered ruthenium catalyst; phenyltriazolyl bromoindanol crystal structure absolute configuration.
In the presence of a tethered Ru-TsDPEN complex, ketones with α-nitrogen heterocycle substituents such as I underwent diastereoselective and enantioselective dynamic kinetic resolution and transfer hydrogenation reactions with triethylamine and formic acid in dichloromethane for 6 h at 27° to yield cis-azolyl cycloalkanols such as II. Using the method, a nonracemic antileishmanial agent and a nonracemic ionic liquid were prepared The structure and absolute configuration of a (phenyltriazolyl)bromoindanol were determined by X-ray crystallog.
Organic Letters published new progress about Azoles Role: RCT (Reactant), SPN (Synthetic Preparation), RACT (Reactant or Reagent), PREP (Preparation) (β-hydroxycycloalkyl, β-ketocycloalkyl). 1192620-83-9 belongs to class amides-buliding-blocks, and the molecular formula is C30H31ClN2O2RuS, Reference of 1192620-83-9.
Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics