Narasimhamurthy, Kereyagalahally H.; Chandrappa, Siddappa; Sharath Kumar, Kothanahally S.; Harsha, Kachigere B.; Ananda, Hanumappa; Rangappa, Kanchugarakoppal S. published the artcile< Easy access for the synthesis of 2-aryl 2,3-dihydroquinazolin-4(1H)-ones using gem-dibromomethylarenes as synthetic aldehyde equivalent>, Computed Properties of 112253-70-0, the main research area is quinazolinone dihydro aryl preparation.
One step synthesis of 2,3-dihydroquinazolin-4(1H)-ones I (R = H, Cl, OCH3; R1 = H, Br, Cl, OCH3; Ar = 3-ClC6H4, 4-pyridyl, 4-CF3C6H4, etc.) from gem-dibromomethylarenes ArCH(Br)2 using 2-aminobenzamide is described. Gem-dibromomethylarenes are used as aldehyde equivalent for the efficient synthesis of 2,3-dihydroquinazolin-4(1H)-ones, this synthesis takes shorter reaction time with quick isolation and excellent product yield.
RSC Advances published new progress about Amino amides Role: RCT (Reactant), RACT (Reactant or Reagent). 112253-70-0 belongs to class amides-buliding-blocks, and the molecular formula is C7H7BrN2O, Computed Properties of 112253-70-0.
Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics