Termsung, Natthida;Cheewangkoon, Ratchadawan;Kunasakdakul, Kaewalin published 《First report of septoria steviae causing stevia leaf spot in Thailand》 in 2021. The article was appeared in 《Journal of Phytopathology》. They have made some progress in their research.Category: amides-buliding-blocks The article mentions the following:
Stevia leaf spot is present in stevia production fields in Chiang Mai, Thailand. The disease was characterized by distinct lesions with angular chlorotic halos that result in defoliation. Based on morphol. characters and sequence anal. of the rDNA internal transcribed spacers (ITS1-5.8S-ITS2 = ITS), rDNA 28S subunit (LSU) and RNA polymerase II second largest subunit (RPB2) genes, the pathogen was identified as Septoria steviae. Pathogenicity tests proved Koch’s postulates, supporting S. steviae as the causal agent of stevia leaf spot in Stevia rebaudiana Bertoni. Mancozeb, chlorothalonil, difenoconazole and azoxystrobin significantly inhibited mycelial growth of S. steviae under in vitro conditions at label the recommended concentrations To our knowledge, this is the first report of Septoria leaf spot disease on stevia caused by S. steviae in Thailand. And N,2-Dihydroxybenzamide (cas: 89-73-6) was used in the research process.
N,2-Dihydroxybenzamide(cas: 89-73-6) is a hydroxamic acid that inhibits the activity of p-hydroxybenzoic acid (PHBA) reductase, an enzyme involved in the conversion of PHBA to benzoic acid. Category: amides-buliding-blocks The compound has been shown to inhibit mitochondrial membrane potential and mitochondrial functions, leading to cell death.
Reference:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics