Chew, Renta Jonathan; Wills, Martin published the artcile< Exploitation of differential electronic densities for the stereoselective reduction of ketones bearing a masked amino surrogate>, Application In Synthesis of 1192620-83-9, the main research area is phthalimidyl ketoether preparation ruthenium catalyst enantioselective transfer hydrogenation; ether alc phthalimidyl preparation.
A tethered ruthenium-TsDPEN catalyst was employed for the facile catalytic asym. reduction of α-phthalimyl-α’-ketoethers under mild conditions. Leveraging exclusively on the contrasting electronic densities on the heteroatoms, a series of enantioenriched phthalimyl ether alcs. were obtained in generally good stereoselectivities from this challenging class of substrate. Subsequent transformation into highly valuable chiral β-amino alcs. was demonstrated to take place without significant losses in yield and optical purity.
Journal of Catalysis published new progress about Alcohols Role: RCT (Reactant), SPN (Synthetic Preparation), RACT (Reactant or Reagent), PREP (Preparation). 1192620-83-9 belongs to class amides-buliding-blocks, and the molecular formula is C30H31ClN2O2RuS, Application In Synthesis of 1192620-83-9.
Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics