Palo-Nieto, Carlos;Afewerki, Samson;Anderson, Mattias;Tai, Cheuk-Wai;Berglund, Per;Cordova, Armando published 《Integrated Heterogeneous Metal/Enzymatic Multiple Relay Catalysis for Eco-Friendly and Asymmetric Synthesis》. The research results were published in《ACS Catalysis》 in 2016.Recommanded Product: 2444-46-4 The article conveys some information:
Organic synthesis is in general performed using stepwise transformations where isolation and purification of key intermediates is often required prior to further reactions. Herein we disclose the concept of integrated heterogeneous metal/enzymic multiple relay catalysis for eco-friendly and asym. synthesis of valuable mols. (e.g., amines and amides) in one-pot using a combination of heterogeneous metal and enzyme catalysts. Here reagents, catalysts, and different conditions can be introduced throughout the one-pot procedure involving multistep catalytic tandem operations. Several novel cocatalytic relay sequences (reductive amination/amidation, aerobic oxidation/reductive amination/amidation, reductive amination/kinetic resolution and reductive amination/dynamic kinetic resolution) were developed. They were next applied to the direct synthesis of various biol. and optically active amines or amides in one-pot from simple aldehydes, ketones, or alcs., resp.N-Vanillylnonanamide (cas: 2444-46-4) were involved in the experimental procedure.
N-Vanillylnonanamide(cas:2444-46-4) is also called pelargonic acid vanillylamide or PAVA.Recommanded Product: 2444-46-4 Similar to capsaicin, nonivamide can activate the TRPV1 receptor, thus, stimulate the firing rate of dopaminergic neurons in the ventral tegmental area of the brain and to increase the expression of the serotonin receptor gene HTR2A.
Reference:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics