Liu, Sujing;Zhou, Jun;Ma, Xuanxuan;Liu, Ying;Ma, Xing;Xia, Chuanhai published 《Ecotoxicity and preliminary risk assessment of nonivamide as a promising marine antifoulant》. The research results were published in《Journal of Chemistry》 in 2016.Category: amides-buliding-blocks The article conveys some information:
The unclear environmental performance of nonivamide limits its application as a marine antifoulant. In this study, the natural degradation of nonivamide was studied in seawater and tap water. The half-life was 5.8 d, 8.8 d, 12.2 d, and 14.7 d in seawater and tap water in photolysis and biolysis, resp. Furthermore, the ecotoxicity of nonivamide was assessed using marine microalgae, Chlorella vulgaris and Platymonas sp.; EC50,6 d values on the growth of Chlorella vulgaris and Platymonas sp. were 16.9 mg L-1 and 19.21 mg L-1, resp. The toxicity and environmental risk of nonivamide on microalgae were significantly decreased due to the natural degradation in seawater. To complete the study, the researchers used N-Vanillylnonanamide (cas: 2444-46-4) .
N-Vanillylnonanamide(cas:2444-46-4) is also called pelargonic acid vanillylamide or PAVA.Category: amides-buliding-blocks Similar to capsaicin, nonivamide can activate the TRPV1 receptor, thus, stimulate the firing rate of dopaminergic neurons in the ventral tegmental area of the brain and to increase the expression of the serotonin receptor gene HTR2A.
Reference:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics