Recommanded Product: 2444-46-4《Exhaled breath condensate methods adapted from human studies using longitudinal metabolomics for predicting early health alterations in dolphins》 was published in 2017. The authors were Borras, Eva;Aksenov, Alexander A.;Baird, Mark;Novick, Brittany;Schivo, Michael;Zamuruyev, Konstantin O.;Pasamontes, Alberto;Parry, Celeste;Foutouhi, Soraya;Venn-Watson, Stephanie;Weimer, Bart C.;Davis, Cristina E., and the article was included in《Analytical and Bioanalytical Chemistry》. The author mentioned the following in the article:
Monitoring health conditions is essential to detect early asymptomatic stages of a disease. To achieve this, blood, urine and breath samples are commonly used as a routine clin. diagnostic. These samples offer the opportunity to detect specific metabolites related to diseases and provide a better understanding of their development. Although blood samples are commonly used routinely to monitor health, the implementation of a relatively noninvasive technique, such as exhaled breath condensate (EBC) anal., may further benefit the well-being of both humans and other animals. EBC anal. can be used to track possible phys. or biochem. alterations caused by common diseases of the bottlenose dolphin (Tursiops truncatus), such as infections or inflammatory-mediated processes. The authors used an untargeted metabolomic method with liquid chromatog.-mass spectrometry anal. of EBC samples to determine biomarkers related to disease development. Five dolphins under human care were followed up for 1 yr. The authors collected paired blood, phys. examination information, and EBC samples. The authors then statistically correlated this information to predict specific health alterations. Three dolphins provided promising case study information about biomarkers related to cutaneous infections, respiratory infections, dental disease, or hormonal changes (pregnancy). The use of complementary liquid chromatog. platforms, with hydrophilic interaction chromatog. and reverse-phased columns, allowed the authors to detect a wide spectrum of EBC biomarker compounds that could be related to these health alterations. Moreover, these two anal. techniques not only provided complementary metabolite information but in both cases they also provided promising diagnostic information for these health conditions. [Figure not available: see fulltext.].N-Vanillylnonanamide (cas: 2444-46-4) were involved in the experimental procedure.
N-Vanillylnonanamide(cas:2444-46-4) is a capsaicin analog that has been used to study the effects of capsaicin on energy metabolism and bowel disease.Recommanded Product: 2444-46-4 It has been shown to be effective in the treatment of bowel disease, by inhibiting the production of proinflammatory cytokines and prostaglandins.
Reference:
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