N′Diaye, Katharina;Debong, Marcel;Behr, Juergen;Dirndorfer, Sebastian;Duggan, Tara;Beusch, Anja;Schlagbauer, Verena;Dawid, Corinna;Loos, Helene M.;Buettner, Andrea;Lang, Roman;Hofmann, Thomas published 《Dietary Piperine is Transferred into the Milk of Nursing Mothers》. The research results were published in《Molecular Nutrition & Food Research》 in 2021.Electric Literature of C17H27NO3 The article conveys some information:
The diet of breastfeeding mothers could bring nurslings into contact with flavor compounds putatively contributing to early sensory programming of the infant. The study investigates whether tastants from a customary curry dish consumed by mothers are detectable in their milk afterwards and can be perceived by the infant. Sensory evaluation identifies pungency as the dominating taste impression of the curry dish. Its ingredients of chili, pepper, and ginger suggest the flavor compounds capsaicin, piperine, and 6-gingerol as anal. targets. Breastfeeding mothers are recruited for an intervention trial involving the consumption of the curry dish and subsequent collection of milk samples for flavor compound anal. Targeted and untargeted mass spectrometric (MS)- investigations identify exclusively piperine as an intervention-derived compound in human milk. However, concentrations are below the human taste threshold. Piperine from pepper-containing foods transfers into the mothers milk within 1 h and is delivered to the nursling. Concentrations of 50 and 200 nM of piperine are 70-350 times below the human taste threshold, but TRPV1 (Transient Receptor Potential Vanilloid-1 ion channel) desensitization through frequent exposure to sub-taste-threshold concentrations could contribute to an increased tolerance at a later age. The experimental procedure involved many compounds, such as N-Vanillylnonanamide (cas: 2444-46-4) .
N-Vanillylnonanamide(cas:2444-46-4) has antifouling properties.Electric Literature of C17H27NO3 It acts as an nicotinamide adenine dinucleotide phosphate (NADPH) inhibitor.N-Vanillylnonanamide has been used for the preparation of spicules.
Reference:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics