Ward, Cassandra L.;Allen, Matthew J.;Lutter, Jacob C. published 《Hexa-μ-acetato-chlorido(μ-N,2-dioxodobenzene-1-carboximidato)-μ3-oxido-tetrairon(III)-water (1/1) and hexa-μ-acetato-(μ-N,2-dioxodobenzene-1-carboximidato)fluorido-μ3-oxido-tripyridinetetrairon(III)-pyridine-water (1/1/0.24)》 in 2021. The article was appeared in 《Acta Crystallographica, Section E: Crystallographic Communications》. They have made some progress in their research.Application In Synthesis of N,2-Dihydroxybenzamide The article mentions the following:
The title compounds, [Fe4(C2H3O2)6(C7H4O3)FO(C5H5N)3]·C5H5N·0.24H2O (1-F) and [Fe4(C2H3O2)6(C7H4O3)ClO(C5H5N)3]·H2O (1-Cl) were synthesized using a self-assembly reaction in methanol and pyridine with stoichiometric addition of salicylhydroxamic acid , acetic acid (HOAc), and the appropriate ferric halide salt. The compounds crystallize as solvates, where 1-F has one pyridine mol. that is disordered about a twofold axis and one water mol. with an occupancy of 0.24 (2); and 1-Cl has one water mol. that is disordered over two sites with occupancies of 0.71 (1) and 0.29 (1). The space groups for each analog differ as 1-F crystallizes in Fdd2 while 1-Cl crystallizes in P21. The difference in packing is due to changes in the intermol. interactions involving the different halides. The two mols. are mostly isostructural, differing only by the torsion of the pyrine ligands and slight orientation changes in the acetate ligands. All of the iron(III) ions are in six-coordinate octahedral ligand field geometries but each one exhibits a unique coordination environment with various numbers of O (four to six) and N (nought to two) atom donors. Bond-valence sums confirm each iron is trivalent. The hydroximate ligand is bound to three iron(III) ions using a fused chelate motif similar to those in metallacrown compounds The experimental procedure involved many compounds, such as N,2-Dihydroxybenzamide (cas: 89-73-6) .
N,2-Dihydroxybenzamide(cas: 89-73-6) has also been shown to be active against wild-type strains of Candida glabrata, but not against resistant mutants. Application In Synthesis of N,2-Dihydroxybenzamide This drug may have therapeutic potential for bone cancer and metabolic disorders such as obesity.
Reference:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics