Jupudi, Srikanth;Jubie, S.;Deepika, N. P.;Dhanabal, S. P. published 《A new pyrimidine alkaloid from the roots of Tadehagi triquetrum (L.) H.Ohashi》 in 2021. The article was appeared in 《Natural Product Research》. They have made some progress in their research.Electric Literature of C22H43NO The article mentions the following:
Tadehagi triquetrum (L.) H. Ohashi, also known as Desmodium triquetrum (Fabaceae) is the most important plant in the herbal remedies. The present study focus on the isolation, in-silico and in-vitro studies of the two alkaloids (5-(4-[(methylcarbamoyl) amino]-2-oxopyrimidin-1(2H)-yl) tetrahydrofuran-2-yl) Me Me carbamate (I) is a novel alkaloid and 13-Docosenamide is a known alkaloid. The chem. structures of compounds have been elucidated based on comprehensive techniques like GCMS, IR and NMR. In order to know the mol. mechanisms for the two compounds, in silico mol. docking study has been performed. Both compounds have shown perfect binding affinity to the enzymes TNFα, IL-4, IL-13 and 5 LOX Enzyme. The compounds also exhibited comparable G-scores and Glide energy values in comparison with the standard dexamethasone. In addition both the compounds have been tested for in vitro antioxidant assay by using ABTS and DPPH method and the results were compared with standard ascorbic acid. To complete the study, the researchers used cis-13-Docosenamide (cas: 112-84-5) .
cis-13-Docosenoamide(cas: 112-84-5) is a primary fatty amide resulting from the formal condensation of the carboxy group of erucic acid with ammonia.Electric Literature of C22H43NO It is commonly used as a slip additive in the plastic manufacturing industry.
Reference:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics