Bozhenkov, G. V.; Savosik, V. A.; Klyba, L. V.; Zhanchipova, E. R.; Mirskova, A. N.; Levkovskaya, G. G. published an article about the compound: 3-(Chloromethyl)-1-methyl-1H-pyrazole( cas:84547-64-8,SMILESS:CN1N=C(CCl)C=C1 ).Application In Synthesis of 3-(Chloromethyl)-1-methyl-1H-pyrazole. Aromatic heterocyclic compounds can be classified according to the number of heteroatoms or the size of the ring. The authors also want to convey more information about this compound (cas:84547-64-8) through the article.
Regioselective heterocyclization of chlorovinyl ketones R1COCH:C(R2)Cl (R1 = Me, R2 = H; R1 = n-Pr, R2 = H, Cl; R1 = CH2Cl, R2 = H) with 1,1-dialkyl-hydrazines NH2N(R3)2 (R3 = Me, n-Bu) to pyrazoles I involved intermediate formation of the corresponding dialkylhydrazones II. The mass spectrum fragmentation pattern of chlorine-containing pyrazoles I (R1 = CH2Cl, R2 = H, R3 = Me; R1 = n-Pr, R2 = Cl, R3 = Me) depended on the position of the halogen atom.
《1-Alkylpyrazoles and 1-alkyl-5-chloropyrazoles from halovinyl ketones and 1,1-dialkylhydrazines》 provides a strategy for the preparation of materials with excellent comprehensive properties, which is conducive to broaden the application field of this compound(3-(Chloromethyl)-1-methyl-1H-pyrazole)Application In Synthesis of 3-(Chloromethyl)-1-methyl-1H-pyrazole.
Reference:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics