Epoxy compounds usually have stronger nucleophilic ability, because the alkyl group on the oxygen atom makes the bond angle smaller, which makes the lone pair of electrons react more dissimilarly with the electron-deficient system. Compound: 3-(Chloromethyl)-1-methyl-1H-pyrazole, is researched, Molecular C5H7ClN2, CAS is 84547-64-8, about Synthesis of pyrazole derivatives from 1,1-dimethylhydrazine and chlorovinyl ketones.Recommanded Product: 3-(Chloromethyl)-1-methyl-1H-pyrazole.
The reaction of accessible 2-chlorovinyl Me ketones with 1,1-dimethylhydrazine gave pyrazole derivatives in high yields. 1,1,1-Trimethylhydrazinium chloride was isolated as second product of this reaction in high yield.
Compound(84547-64-8)Recommanded Product: 3-(Chloromethyl)-1-methyl-1H-pyrazole received a lot of attention, and I have introduced some compounds in other articles, similar to this compound(3-(Chloromethyl)-1-methyl-1H-pyrazole), if you are interested, you can check out my other related articles.
Reference:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics