The three-dimensional configuration of the ester heterocycle is basically the same as that of the carbocycle. Compound: 3-(Chloromethyl)-1-methyl-1H-pyrazole(SMILESS: CN1N=C(CCl)C=C1,cas:84547-64-8) is researched.HPLC of Formula: 4385-62-0. The article 《New synthesis and properties of 3-alkyl-, 3-chloroalkyl-, 3-perfluoroalkyl-, and 3-aryl-1-methyl-5-halopyrazoles from chloro(bromo)vinyl ketones and N,N-dimethylhydrazine》 in relation to this compound, is published in Russian Journal of Organic Chemistry (Translation of Zhurnal Organicheskoi Khimii). Let’s take a look at the latest research on this compound (cas:84547-64-8).
A new regioselective heterocyclization was revealed in the reaction of 2-chloro- and 2,2-dichloro(bromo)vinyl ketones with N,N-dimethylhydrazine to afford 3-substituted 1-methyl-5-halopyrazoles. The reaction is accompanied by elimination of Me halide and formation of up to 90% of N,N,N-trimethylhydrazinium halide as the second product.
If you want to learn more about this compound(3-(Chloromethyl)-1-methyl-1H-pyrazole)Safety of 3-(Chloromethyl)-1-methyl-1H-pyrazole, you may wish to communicate with the author of the article,or consult the relevant literature related to this compound(84547-64-8).
Reference:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics