The reaction of an aromatic heterocycle with a proton is called a protonation. One of articles about this theory is 《New synthesis and properties of 3-alkyl-, 3-chloroalkyl-, 3-perfluoroalkyl-, and 3-aryl-1-methyl-5-halopyrazoles from chloro(bromo)vinyl ketones and N,N-dimethylhydrazine》. Authors are Levkovskaya, G. G.; Bozhenkov, G. V.; Larina, L. I.; Mirskova, A. N..The article about the compound:3-(Chloromethyl)-1-methyl-1H-pyrazolecas:84547-64-8,SMILESS:CN1N=C(CCl)C=C1).SDS of cas: 84547-64-8. Through the article, more information about this compound (cas:84547-64-8) is conveyed.
A new regioselective heterocyclization was revealed in the reaction of 2-chloro- and 2,2-dichloro(bromo)vinyl ketones with N,N-dimethylhydrazine to afford 3-substituted 1-methyl-5-halopyrazoles. The reaction is accompanied by elimination of Me halide and formation of up to 90% of N,N,N-trimethylhydrazinium halide as the second product.
There is still a lot of research devoted to this compound(SMILES：CN1N=C(CCl)C=C1)SDS of cas: 84547-64-8, and with the development of science, more effects of this compound(84547-64-8) can be discovered.
Reference:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics