Recently I am researching about DIRECT AMIDE FORMATION; MECHANISTIC INSIGHTS; BOND FORMATION; BORONIC ACIDS; CONDENSATION; ALPHA; CYCLOADDITIONS; ACTIVATION; CHEMISTRY; AMINES, Saw an article supported by the JSPS KAKENHIMinistry of Education, Culture, Sports, Science and Technology, Japan (MEXT)Japan Society for the Promotion of ScienceGrants-in-Aid for Scientific Research (KAKENHI) [16K18850, 19K07000, 17K08218]; Kitasato University. Published in AMER CHEMICAL SOC in WASHINGTON ,Authors: Shimada, N; Hirata, M; Koshizuka, M; Ohse, N; Kaito, R; Makino, K. The CAS is 91-00-9. Through research, I have a further understanding and discovery of Diphenylmethanamine. Formula: C13H13N
The direct catalytic dehydrative amidation of beta-hydroxycarboxylic acids with amines is described. A biphenyl-based diboronic acid anhydride with a B-O-B skeleton is shown to be an exceptionally effective catalyst for the reaction, providing beta-hydroxycarboxylic amides in high to excellent yields with a low catalyst loading (minimum of 0.01 mol %, TON up to 7,500). This hydroxy-directed amidation shows excellent chemoselectivity and is applicable to gram-scale drug synthesis.
Formula: C13H13N. Bye, fridends, I hope you can learn more about C13H13N, If you have any questions, you can browse other blog as well. See you lster.
Reference:
Amide – Wikipedia,
,Amide – an overview | ScienceDirect Topics