An article Iodinated Choline Transport-Targeted Tracers WOS:000603401900045 published article about MAGNETIC-RESONANCE-SPECTROSCOPY; POSITRON-EMISSION-TOMOGRAPHY; PROSTATE-CANCER; RADIATION-DOSIMETRY; LUNG-CANCER; IN-VITRO; METABOLISM; F-18-FLUOROCHOLINE; DIAGNOSIS; CELLS in [Svec, Pavel; Kucka, Jan; Sedlacek, Ondrej; Kolouchova, Kristyna; Groborz, Ondrej; Loukotova, Lenka; Konefal, Rafal L.; Hruby, Martin] CAS, Inst Macromol Chem, Prague 16206 6, Czech Republic; [Svec, Pavel] Charles Univ Prague, Fac Sci, Dept Phys & Macromol Chem, Prague 12843 2, Czech Republic; [Novy, Zbynek; Petrik, Milos; Liskova, Barbora; Medvedikova, Martina; Hajduch, Marian] Palacky Univ Olomouc, Fac Med & Dent, Inst Mol & Translat Med, Olomouc 77900, Czech Republic; [Kuchar, Martin] Univ Chem & Technol, Forens Lab Biol Act Subst, Prague 16000, Czech Republic in 2020, Cited 58. The Name is 2-(4-Aminophenyl)ethanol. Through research, I have a further understanding and discovery of 104-10-9. Application In Synthesis of 2-(4-Aminophenyl)ethanol
We present a novel series of radioiodinated tracers and potential theranostics for diseases accompanied by pathological function of proteins involved in choline transport. Unlike choline analogues labeled with C-11 or F-18 that are currently used in the clinic, the iodinated compounds described herein are applicable in positron emission tomography, single-photon emission computed tomography, and potentially in therapy, depending on the iodine isotope selection. Moreover, favorable half-lives of iodine isotopes result in much less challenging synthesis by isotope exchange reaction. Six of the described compounds were nanomolar ligands, and the best compound possessed an affinity 100-fold greater than that of choline. Biodistribution data of I-125-labeled ligands in human prostate carcinoma bearing (PC-3) mice revealed two compounds with a biodistribution profile superior to that of [F-18]fluorocholine.
Application In Synthesis of 2-(4-Aminophenyl)ethanol. About 2-(4-Aminophenyl)ethanol, If you have any questions, you can contact Svec, P; Novy, Z; Kucka, J; Petrik, M; Sedlacek, O; Kuchar, M; Liskova, B; Medvedikova, M; Kolouchova, K; Groborz, O; Loukotova, L; Konefal, RL; Hajduch, M; Hruby, M or concate me.
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Amide – Wikipedia,
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