Related Products of 6973-09-7,Some common heterocyclic compound, 6973-09-7, name is 5-Amino-2-methylbenzenesulfonamide, molecular formula is C7H10N2O2S, traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc, below Introduce a new synthetic route.
A mixture of 5-amino-2-methylbenzenesulfonamide (14.4 mg, 0.077 mmol) and compound 13a (20 mg, 0.077 mmol) in 1-butanol (1.5 mL) was subjected to ultrasonic reaction at 200 ° C for 30 minutes. The reaction vial was cooled to room temperature and the solvent was evaporated under vacuum. The crude product was purified by flash column chromatography (MeOH: DCM = 1: 20) to give compound MKP101 (20.1 mg, 0.0492 mmol, 63.9percent).
These compound has a wide range of applications. It is believed that with the continuous development of the source of the synthetic route 5-Amino-2-methylbenzenesulfonamide, its application will become more common.
Reference:
Patent; CHUNG ANG University industry Academic Cooperation Foundation; Min, Kyung-Hoon; (30 pag.)KR2016/147170; (2016); A;,
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