In the chemical reaction process, reaction time, type of solvent, can easily affect the result of the reaction, thereby determining the yield and properties of the reaction product. An updated downstream synthesis route of 24243-71-8 as follows. COA of Formula: C3H9NO2S
In DMSO were dissolved 2,3-dichloroquinoxaline (5.00 g, 25.1 mmol) and propane-1-sulfonamide (3.09 g, 25.1mmol). Potassium carbonate (3.47 g, 25.1 mmol) was added and the mixture was stirred at 150C for 1 hour. A 1%aqueous acetic acid solution was added to the mixture and the mixture was stirred at room temperature for 3 hours. Theprecipitated solid was separated by filtration and the obtained solid was washed with water. The separated solid wasthen purified by slurrying in diisopropyl ether to give compound AA (6.01 g, 84% yield).
According to the analysis of related databases, 24243-71-8, the application of this compound in the production field has become more and more popular.
Reference:
Patent; Kyowa Hakko Kirin Co., Ltd.; KANAI, Toshimi; UCHIDA, Kenji; HONMA, Masakazu; FUKUDA, Yuichi; (51 pag.)EP2781517; (2014); A1;,
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