Related Products of 50487-72-4,Some common heterocyclic compound, 50487-72-4, name is N,N-Diallyl-4-methylbenzenesulfonamide, molecular formula is C13H17NO2S, traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc, below Introduce a new synthetic route.
General procedure: The general procedure for metathesis reactions with ruthenium carbenes 10 was performed as follows: a certain amount of ruthenium carbene catalyst 10 (0.0005-0.0125mmol) and a solution of the substrate (0.5mmol) in 1.0mL dry CH2Cl2 (or toluene) was mixed in a reaction flask under nitrogen. The reaction mixture was stirred for 0.3-24h. At the end of the reaction (monitored by thin-layer chromatography (TLC)), the catalysts were separated by silica gel chromatography using CH2Cl2 as the eluent to remove trace amounts of Ru residues. Conversions were estimated by 1H NMR spectroscopy and obtained by comparing the ratios of the integrals of the starting materials with those of products. The catalytic activities of ruthenium carbene 10 for a variety of substrates are shown in Table 1.
These compound has a wide range of applications. It is believed that with the continuous development of the source of the synthetic route N,N-Diallyl-4-methylbenzenesulfonamide, its application will become more common.
Reference:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics