Synthetic Route of 2227-79-4,Some common heterocyclic compound, 2227-79-4, name is Benzothioamide, molecular formula is C7H7NS, traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc, below Introduce a new synthetic route.
1. 3 Dichloroacetone (170 mmol), thiobenzamide (150 mmol), ethanol (150 mL) and THF (75 mL) was reacted for 5-8 hours under refluxed and stirring and conditions. The most of the solvent was removed, cooled, the reaction solution was poured into ice water, extracted with ethyl acetate, washed with the organic phase, dried over anhydrous sodium sulfate, and the solvent was removed under reduced pressure to obtain a yellow liquid title 28 g
The synthetic route of 2227-79-4 has been constantly updated, and we look forward to future research findings.
Reference:
Patent; Huang, Danling; Hunan Research Institute of Chemical Industry ltd; Liu, Aiping; Huang, Mingzhi; Li, Jianming; Wang, xiaoguang; Liu, Weidong; Chen, Xiao Yang; He, Lian; Xiang, Jun; Pei, Hui; (24 pag.)CN106608873; (2017); A;,
Amide – Wikipedia,
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