In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 563-83-7, name is Isobutyramide belongs to amides-buliding-blocks compound, it is a common compound, a new synthetic route is introduced below. Safety of Isobutyramide
A solution containing isobutyramide (10 g, 115 mmol) in THF (250 mL) was treated with phosphorous pentasulfide (4.1 g, 9.22 mmol), stirred at 25 C. for 64 hours, concentrated and partitioned between ethyl acetate and water. The organic phase was washed with brine and dried over MgSO4, filtered and concentrated to give the title compound (8.6 g, 73% yield), which was used without further purification.
The synthetic route of 563-83-7 has been constantly updated, and we look forward to future research findings.
Reference:
Patent; DeGoey, David A.; Flentge, Charles A.; Flosi, William J.; Grampovnik, David J.; Kempf, Dale J.; Klein, Larry L.; US2005/131017; (2005); A1;,
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