Application of 6292-59-7, A common heterocyclic compound, 6292-59-7, name is 4-(tert-Butyl)benzenesulfonamide, molecular formula is C10H15NO2S, its traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc, below Introduce a new synthetic route.
EXAMPLE 20 By reacting 4,6-dichloro-5-[(2-methoxy-4-methyl)phenoxy]pyrimidine with p-t-butylbenzenesulfonamide and thereafter with ethylene glycol Na there was obtained p-t-butyl-N-[6-(2-hydroxyethoxy)-5-[(2-methoxy-p-tolyl)oxy]-4-pyrimidinyl]benzenesulfonamide as a solid.
The synthetic route of 6292-59-7 has been constantly updated, and we look forward to future research findings.
Reference:
Patent; Hoffmann-La Roche Inc.; US5292740; (1994); A;,
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