617-36-7, name is Ethyl 2-amino-2-oxoacetate, belongs to amides-buliding-blocks compound, is considered to be a conventional heterocyclic compound, which is widely used in drug synthesis. The chemical synthesis route is as follows. name: Ethyl 2-amino-2-oxoacetate
4′-Nitro-2-bromoacetophenone (6.100 g, 25 MMOL) and ethyl thioxamate (3.460 g, 26 MMOL) were dissolved in MeOH (20 mL) and the solution was refluxed for 1 h. After cooling to room temperature, the precipitated solid was collected by filtration, washed with cold MEOH and dried under vacuum (5.15 g, 75% yield).
The synthetic route of 617-36-7 has been constantly updated, and we look forward to future research findings.
Reference:
Patent; BOEHRINGER INGELHEIM INTERNATIONAL GMBH; BOEHRINGER INGELHEIM PHARMA GMBH & CO KG; WO2004/65367; (2004); A1;,
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