Adding a certain compound to certain chemical reactions, such as: 618-48-4, name is 3-Chlorobenzamide, belongs to amides-buliding-blocks compound, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 618-48-4, SDS of cas: 618-48-4
General procedure: DDQ (20 mol%, 9.08 mg, 0.04 mmol) and BPO (20 mol%,9.69 mg, 0.04 mmol) were added to a mixture of 1,3-diarylpropene1 (0.24 mmol) and substrate 2 (0.2 mmol) in CH3NO2 (1 mL). Thereaction was carried out at 100 C under an oxygen atmosphere(oxygen balloon) for 24 h. The resulting mixture was purified by flashcolumn chromatography on silica gel (petroleum ether:ethyl acetate =10:1-20:1) to give the desired pure product 3a-k.
If you are interested in these compounds, you can also browse my other articles.Thank you for taking the time to read this article. I hope you enjoyed it.
Reference:
Article; Cheng, Dongping; Zhou, Xiayi; Yuan, Kun; Yan, Jizhong; Journal of Chemical Research; vol. 40; 3; (2016); p. 127 – 129;,
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics