Application of 28797-48-0, In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 28797-48-0, name is 11-(2-Chloroacetyl)-5H-benzo[e]pyrido[3,2-b][1,4]diazepin-6(11H)-one belongs to amides-buliding-blocks compound, it is a common compound, a new synthetic route is introduced below.
EXAMPLE 36 11-[[4-[2-[2-(Diethylamino)ethoxy]ethyl]-1-piperidinyl]-acetyl]-5,11-dihydro-6H-pyrido[2,3-b][1,4]benzodiazepin-6-one Prepared analogously to Example 1 from 11-(chloroacetyl)-5,11-dihydro-6H-pyrido[2,3-b][1,4]benzodiazepin-6-one and 4-[2-[2-(diethylamino)ethoxy]ethyl]piperidine (Bp0.009 mmHg 96-102 C.) in a yield of 46% of theory. Colourless crystals, m.p. 130-131 C. (acetonitrile).
The synthetic route of 11-(2-Chloroacetyl)-5H-benzo[e]pyrido[3,2-b][1,4]diazepin-6(11H)-one has been constantly updated, and we look forward to future research findings.
Reference:
Patent; Dr. Karl Thomae, GmbH; US5175158; (1992); A;,
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