Adding a certain compound to certain chemical reactions, such as: 6292-59-7, name is 4-(tert-Butyl)benzenesulfonamide, belongs to amides-buliding-blocks compound, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 6292-59-7, Product Details of 6292-59-7
Process for conversion of compound (2) to (3) (stage 2)A mixture of DMSO (10 vol), potassium carbonate (1.2 eq), 4-tert-butyl phenyl sulfonamide (1 eq) and compound (2) (1 eq) was heated at 1200C for 10 hours. After completion of the reaction, water (25 vol) was added to the reaction mixture, the reaction mixture was acidified with a solution of tartaric acid (1.8 eq) in water (25 vol) to pH 3, and the precipitated solid was filtered under vacuum and dried under vacuum (lOmbar) at 500C for 2 hours. The product (compound (3)) was obtained as a light brown solid (molar yield = 100percent).
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Reference:
Patent; GENERICS [UK] LIMITED; MYLAN INDIA PRIVATE LIMITED; WO2009/98517; (2009); A1;,
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics