Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 698-67-9, name is 4-Bromobenzamide, This compound has unique chemical properties. The synthetic route is as follows., Computed Properties of C7H6BrNO
The under nitrogen atmosphere, 4-bromobenzamide (597 mg, 3 mmol, 1.0 eq.) was dissolved in 25 ml of triethylamine, and then added trimethylsilylacetylene (2.94 g, 30 mmol, 10 eq), bis(triphenylphosphine) palladium dichloride (421 mg, 0.6 mmol, 0.2 eq.), cuprous iodide (228 mg, 1.2 mmol, 0.4 eq.). The reaction mixture was heated to 50 °C with stirring. Reaction was diluted with ethyl acetate release, filtered through Celite, washed twice with ethyl acetate, and the filtrate was concentrated in vacuo, the residue was purified by to give the title compound as a brown oil was purified by column 4-trimethylsilylethynylbenzamide (780 mmol g, crude).
According to the analysis of related databases, 698-67-9, the application of this compound in the production field has become more and more popular.
Reference:
Patent; Guangzhou Kaisheng Beite Pharmaceutical Co., Ltd.; Cai, Xiong; Qian, Changgeng; Liu, Bin; Li, Junqi; Lin, Mingsheng; Qing, Yuanhui; Weng, Yunwo; Wang, Yanyan; Xue, Weicai; You, Huajin; Zhou, Shiqing; (67 pag.)CN105622638; (2016); A;,
Amide – Wikipedia,
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