Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 71510-95-7, name is Ethyl 3-(methylamino)-3-oxopropanoate, This compound has unique chemical properties. The synthetic route is as follows., name: Ethyl 3-(methylamino)-3-oxopropanoate
General procedure: In a round bottom flask, unsaturated aldehyde 2 (0.25 mmol, 1 equiv), amidomalonate 1 (0.3 mmol, 1.2 equiv), catalyst (0.05 mmol, 20% mol), and KOAc (0.3 mmol, 1.2 equiv) were added sequentially in 1 mL of 2,2,2-trifluoroethanol. The reaction was stirred at room temperature overnight. Then the crude was purified by column chromatography to furnish piperidine adducts 3.
Chemical properties determine the actual use. Each compound has specific chemical properties and uses. We look forward to more synthetic routes in the future to expand reaction routes of 71510-95-7.
Reference:
Article; ?ihalova, Sylva; Valero, Guillem; Schimer, Ji?i; Humpl, Marek; Dra?insky, Martin; Moyano, Albert; Rios, Ramon; Vesely, Jan; Tetrahedron; vol. 67; 46; (2011); p. 8942 – 8950;,
Amide – Wikipedia,
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