Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 75175-77-8, name is 3-(4-Fluorophenyl)-N,N-dimethylacrylamide, This compound has unique chemical properties. The synthetic route is as follows., Application In Synthesis of 3-(4-Fluorophenyl)-N,N-dimethylacrylamide
General procedure: A typical procedure: Amixture of beta-dimethylaminovynil ketone 1a-h (1.0 mmol, 0.175 g), ChCl:TsOH (1:2) (0.519 g), and 3-amino-5-methylthio-1H-1,2,4-triazole 2 (1.2 mmol, 0.156 g) was heated to120 C for 5 min.Water (10 mL) was added, and the resulting product(3) was extracted with chloroform (3 × 10 mL). The organic phaseswere dried over anhydrous Na2SO4 and the solvent was evaporateduntil totally dry in order to obtain the desired triazolopyrimidines(3a-h) in a pure form. The structure of compounds 3a-h was confirmedby 1H, 13C NMR spectroscopy, determination of their melting points, gaschromatography mass spectrometry (GC-MS), high-resolution massspectra (HRMS), and, FT-IR spectra. These data are available in theSupporting Information.
Chemical properties determine the actual use. Each compound has specific chemical properties and uses. We look forward to more synthetic routes in the future to expand reaction routes of 75175-77-8.
Reference:
Article; Martins, Marcos A.P.; Paveglio, Guilherme C.; Munchen, Taiana S.; Meyer, Alexandre R.; Moreira, Dayse N.; Rodrigues, Leticia V.; Frizzo, Clarissa P.; Zanatta, Nilo; Bonacorso, Helio G.; Melo, Paola A.; Krzyzaniak, Sindy R.; Journal of Molecular Liquids; vol. 223; (2016); p. 934 – 938;,
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