Synthetic Route of 2432-99-7, Catalysts allow a reaction to proceed via a pathway that has a lower activation energy than the uncatalyzed reaction. 2432-99-7, Name is 11-Aminoundecanoic acid, SMILES is NCCCCCCCCCCC(O)=O, belongs to amides-buliding-blocks compound. In a article, author is Lin, Hong-Yan, introduce new discover of the category.
Chronic psychological stress is an important public health issue which generates behavioral changes, anxiety, immunosuppression and oxidative damage. Piracetam is a cognitive enhancer, at cellular level it protects from oxidative stress. The aim of this study was to evaluate the effect of psychological stress and of piracetam on circulating mononuclear cells by analyzing the biochemical spectrome using Synchrotron Radiation Fourier Transform Infrared Microspectroscopy (SR-mu FTIR). Rats were exposed for five days to a stressor (cat odor) under oral administration of piracetam (600 mg/kg). SR-mu FTIR analysis showed a decrease in bands associated to the lipids region (2852 cm(-1), 2923 cm(-1) and 2962 cm(-1)) and an increase absorption of the amide I band (1654 cm(-1)) under stress conditions. The principal component analysis showed increase oxidation of lipids (decrease of 3010 cm(-1), 2923 cm(-1) and 2852 cm(-1) bands) as well as proteins denaturation (increase of 1610 cm-1 and 1690 cm(-1) bands) under stress. Piracetam provided protection to polyunsaturated lipids (p <= 0.001) and lipids/proteins ratio (p <= 0.001). Behaviorally, this drug diminished fear and anxiety in stressed animals by the plus maze test (p <= 0.002). However, this drug induced oxidative stress in mononuclear cells from unstressed animals and altered their behavior. (C) 2018 Elsevier B.V. All rights reserved. Synthetic Route of 2432-99-7, The reactant in an enzyme-catalyzed reaction is called a substrate. Enzyme inhibitors cause a decrease in the reaction rate of an enzyme-catalyzed reaction.I hope my blog about 2432-99-7 is helpful to your research.
Reference:
Amide – Wikipedia,
,Amide – an overview | ScienceDirect Topics