Properties and Exciting Facts About (R)-2-Aminopentanedioic acid

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One of the major reasons for studying chemical kinetics is to use measurements of the macroscopic properties of a system, such as the rate of change in the concentration of reactants or products with time. 6893-26-1, Name is (R)-2-Aminopentanedioic acid, formurla is C5H9NO4. In a document, author is Planas, Ferran, introducing its new discovery. HPLC of Formula: https://www.ambeed.com/products/6893-26-1.html.

BACKGROUNDN-Pyridylpyrazole derivatives have received continuous attention in agrochemical research during the last decade owing to their remarkable insecticidal or fungicidal potentials. To look for novel heterocyclic agrochemicals for increasing production of agriculture, a series of novel alpha -aminophosphonate derivatives containing N-pyridylpyrazole moiety were synthesized. RESULTSThe structures of the title compounds were confirmed via melting point, IR, H-1 NMR, C-13 NMR, P-31 NMR, HRMS and elemental analysis. The single crystal structure of diethyl (3-bromo-1-(3-chloropyridin-2-yl)-1H-pyrazol-5-yl)(2,6-dimethylphenylamino)methylphosphonate (compound 12b) was first reported. Moreover, the bioassays displayed that the title compounds exhibited modest or weak insecticidal activities against oriental armyworm at 200 mu gmL(-1). The first investigation on the fungicidal potential of chlorantraniliprole showed no significant activities towards the six tested fungi found in this study, however, most of the title compounds displayed apparent in vitro fungicidal activity against some plant fungi, in particular excellent activities towards Physalospora piricola. Compounds 11a and 11b had EC50 values of 18.8 and 17.4 mu gmL(-1), respectively, which were comparable with that of fungicide control triadimefon (EC50 = 24.7 mu gmL(-1)) against Physalospora piricola. In addition, some compounds exhibited modest in vivo control efficacy at 0.5 mgmL(-1) towards Sclerotinia sclerotiorum (11b: 30.1(1.8)%), Rhizoctonia cerealis (11a: 20.4(+/- 2.1)%; 11b: 30.2(+/- 2.2)%), and Erysiphe graminis (11a: 30.3(+/- 1.8)%; 12d: 40.2(+/- 0.9)%). CONCLUSIONCompounds 11a, 11b and 12d could be promising new lead structures for the development and discovery of novel fungicides towards Physalospora piricola and Erysiphe graminis. The structure-activity relationship (SAR) analysis provided useful guidance and new understanding for the design of novel pyridylpyrazole-containing agrochemicals. (c) 2019 Society of Chemical Industry

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Reference:
Amide – Wikipedia,
,Amide – an overview | ScienceDirect Topics