Enzymes are biological catalysts that produce large increases in reaction rates and tend to be specific for certain reactants and products. 51857-17-1, Name is N-Boc-1,6-Diaminohexane, molecular formula is C11H24N2O2, belongs to amides-buliding-blocks compound. In a document, author is Meng, Xu, introduce the new discover, Quality Control of N-Boc-1,6-Diaminohexane.
Three decahydroisoquinoline alkaloids, lepadins I-K, were isolated from a specimen of Didemnum sp. collected in the Bahamas. The structures of the new compounds were assigned by an integrated analysis of MS, IR, and H-1, C-13, and 2D NMR spectra. Like previously reported lepadins, the structures of the new compounds contain a decahydroquinoline heterocyclic core in lepadin I, and a new variation, an octahydroquinoline in lepadin J, but differ from earlier reported compounds by acylation of the 3-hydroxyl group by a rare 3′-methylthioacrylate. The absolute configuration of lepadin I was solved by interpretation of NOE measurements, and exciton coupled circular dichroism (ECCD) of the corresponding N-p-bromobenzoyl derivative. The latter constitutes a general method for determination of absolute configuration of the entire lepadin family. The configuration of the remote side-chain secondary carbinol was solved by the modified Mosher’s esters method. Lepadin I inhibited butyrylcholineesterase (BuChE, IC50 3.1 mu M), but only weakly inhibited acetylcholineesterase (AChE) (10% at 100 mu M).
Balanced chemical reaction does not necessarily reveal either the individual elementary reactions by which a reaction occurs or its rate law. In my other articles, you can also check out more blogs about 51857-17-1. Quality Control of N-Boc-1,6-Diaminohexane.
Reference:
Amide – Wikipedia,
,Amide – an overview | ScienceDirect Topics