Brief introduction of 52-52-8

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A catalyst don’t appear in the overall stoichiometry of the reaction it catalyzes, but it must appear in at least one of the elementary reactions in the mechanism for the catalyzed reaction. 52-52-8, Name is 1-Aminocyclopentanecarboxylic acid, molecular formula is C6H11NO2. In an article, author is Kulkarni, Pravin S.,once mentioned of 52-52-8, Recommanded Product: 1-Aminocyclopentanecarboxylic acid.

An intramolecular C(sp(3))-H bond functionalization adjacent to an amide nitrogen atom was successfully developed for synthesis of 2-hydroxybenzoxazinone derivatives under environment-friendly conditions. The method featured no metal catalyst, broad substrate scopes and high yields. Besides, a radical mechanism was proposed in the reaction process. Additionally, most of target compounds exhibited potent anti-proliferative activities against MCF-7 and Hela cells. (C) 2017 Published by Elsevier Ltd.

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Reference:
Amide – Wikipedia,
,Amide – an overview | ScienceDirect Topics