Children learn through play, and they learn more than adults might expect. Science experiments are a great way to spark their curiosity, HPLC of Formula: https://www.ambeed.com/products/150-25-4.html150-25-4, Name is 2-(Bis(2-hydroxyethyl)amino)acetic acid, SMILES is OCCN(CCO)CC(O)=O, belongs to amides-buliding-blocks compound. In a article, author is Marczenko, Katherine M., introduce new discover of the category.
In this work, redox/enzyme-responsive fluorescent porous silica (pSiO(2)) nanoparticles (NPs) were constructed for drug delivery. The resultant pSiO(2) NPs have large-pore core and mesoporous shell with size of 75 nm and present high specific surface area (605 m(2) g(-1)). Oxidized glutathione (GSSG) as linker was conjugated on the surfaces of amino-functionalized porous silica (pSiO(2)-NH2) NPs by the amide bonds for redox-responsive drug release. Dox is served as model drugs to evaluate the release performance of carriers. After loading Dox molecules, both carbon dots (CDs) as fluorescent label and hyaluronic acid (HA) as gatekeepers are capped on the surface of carries (pSiO(2)-ss-CDs/HA) so as to endow the delivery system with fluorescent monitoring and enzyme-responsive properties. The pSiO(2)-ss-CDs/HA carriers displayed redox/enzyme-responsive and sustained release behavior. The controlled release of drug from the pSiO(2)-ss-CDs/HA delivery system was realized by the reduction of disulfide bonds in GSSG linker and degrading HA molecules. The incorporated CDs presented novel redox-dependent fluorescence, which could be used to trace the drug release.
Note that a catalyst decreases the activation energy for both the forward and the reverse reactions and hence accelerates both the forward and the reverse reactions. you can also check out more blogs about 150-25-4. HPLC of Formula: https://www.ambeed.com/products/150-25-4.html.
Reference:
Amide – Wikipedia,
,Amide – an overview | ScienceDirect Topics