Related Products of 150-25-4, As an important bridge between the micro and macro material world, chemistry is one of the main methods and means for humans to understand and transform the material world. 150-25-4, Name is 2-(Bis(2-hydroxyethyl)amino)acetic acid, SMILES is OCCN(CCO)CC(O)=O, belongs to amides-buliding-blocks compound. In a article, author is Jerhaoui, Soufyan, introduce new discover of the category.
XimA is a unique amide synthetase that belongs to the ANL superfamily of adenylating enzymes, but with a special structural fold. In order to improve the enzyme promiscuity, we engineered XimA by site-directed mutagenesis at a specific position based on our theoretical model of XimA. Thus, we were able to produce diverse benzopyran derivatives with up to 15 different l-form and d-form amino acid substitutions, catalyzed by several XimA variants. Molecular docking and molecular dynamics simulations conducted for various XimA systems provide further structural insights into the substitution effects of the phenylalanine-201 as an active site residue on protein dynamics and enzyme catalysis.
Related Products of 150-25-4, One of the oldest and most widely used commercial enzyme inhibitors is aspirin, which selectively inhibits one of the enzymes involved in the synthesis of molecules that trigger inflammation. you can also check out more blogs about 150-25-4.
Reference:
Amide – Wikipedia,
,Amide – an overview | ScienceDirect Topics