Synthetic Route of 6027-13-0, As an important bridge between the micro and macro material world, chemistry is one of the main methods and means for humans to understand and transform the material world. 6027-13-0, Name is (S)-2-Amino-4-mercaptobutanoic acid, SMILES is N[C@@H](CCS)C(O)=O, belongs to amides-buliding-blocks compound. In a article, author is Wang, Ya-Li, introduce new discover of the category.
Reducing or eliminating organic solvent use in pharmaceutical manufacturing is perhaps the most effective way to reduce the environmental, health, and safety impacts of drug substance manufacturing. With this in mind, we have developed a process to manufacture an investigational 6-HT4 receptor agonist that is conducted almost entirely in water, including multiple controlled isolations. Key transformations carried out in aqueous media include a benzimidazole cyclization, amide bond formation, reductive amination, and a selective oxidation of an aliphatic alcohol. Compared to the first-generation manufacturing process using organic solvents, the aqueous process described here uses 77% less material inputs, 94% less organic solvent, and, surprisingly, 48% less water, while improving overall yield from 35% to 56%.
Synthetic Route of 6027-13-0, The reactant in an enzyme-catalyzed reaction is called a substrate. Enzyme inhibitors cause a decrease in the reaction rate of an enzyme-catalyzed reaction.I hope my blog about 6027-13-0 is helpful to your research.
Reference:
Amide – Wikipedia,
,Amide – an overview | ScienceDirect Topics