Children learn through play, and they learn more than adults might expect. Science experiments are a great way to spark their curiosity, COA of Formula: https://www.ambeed.com/products/2026-48-4.html2026-48-4, Name is L-Valinol, SMILES is N[C@@H](C(C)C)CO, belongs to amides-buliding-blocks compound. In a article, author is Badoux, Michael, introduce new discover of the category.
The modification of lysine residues with acylating agents has represented a ubiquitous approach to the construction of antibody conjugates, with the resulting amide bonds being robustly stable and clinically validated. However, the conjugates are highly heterogeneous, due to the presence of numerous lysines on the surface of the protein, and greater control of the sites of conjugation are keenly sought. Here we present a novel approach to achieve the targeted modification of lysines distal to an antibody fragment’s binding site, using a disulfide bond as a temporary ‘hook’ to deliver the acylating agent. This cysteine-to-lysine transfer (CLT) methodology offers greatly improved homogeneity of lysine conjugates, whilst retaining the advantages offered by the formation of amide linkages.
Note that a catalyst decreases the activation energy for both the forward and the reverse reactions and hence accelerates both the forward and the reverse reactions. you can also check out more blogs about 2026-48-4. COA of Formula: https://www.ambeed.com/products/2026-48-4.html.
Reference:
Amide – Wikipedia,
,Amide – an overview | ScienceDirect Topics