Synthetic Route of 38256-93-8, Catalysts allow a reaction to proceed via a pathway that has a lower activation energy than the uncatalyzed reaction. 38256-93-8, Name is 2-Methoxy-N-methylethanamine, SMILES is COCCNC, belongs to amides-buliding-blocks compound. In a article, author is Yu, Lu, introduce new discover of the category.
A mild and metal-free DEAD-promoted (DEAD = diethyl azodicarboxylate) oxidative Ugi-type reaction of tertiary amines has been demonstrated. The reaction gives easy access to -amino amides and imides with diverse functional groups in good isolated yields. This Ugi-type approach achieves an unprecedented synthesis of -amino amide analogues with the assistance of dicarboxylic acids, and not water, for the introduction of the carbonyl oxygen atom of the amide moiety. Mechanistic studies indicated that the dicarboxylic acids may readily undergo an intramolecular annulation, instead of the Mumm rearrangement, to give the desired amide with one molecule of anhydride released.
Synthetic Route of 38256-93-8, Each elementary reaction can be described in terms of its molecularity, the number of molecules that collide in that step. The slowest step in a reaction mechanism is the rate-determining step.you can also check out more blogs about 38256-93-8.
Reference:
Amide – Wikipedia,
,Amide – an overview | ScienceDirect Topics