Chemistry is the science of change. But why do chemical reactions take place? Why do chemicals react with each other? The answer is in thermodynamics and kinetics, Category: amides-buliding-blocks, 109425-51-6, Name is Fmoc-His(Trt)-OH, SMILES is O=C(O)[C@H](CC1=CN(C(C2=CC=CC=C2)(C3=CC=CC=C3)C4=CC=CC=C4)C=N1)NC(OCC5C6=C(C7=C5C=CC=C7)C=CC=C6)=O, belongs to amides-buliding-blocks compound. In a document, author is Tang, Rui, introduce the new discover.
The synthesis of a novel mono-anionic phosphino-amide ligand based on a xanthene backbone is reported, togetherr with the corresponding Ga-I complex, (PON)Ga (PON = 4-(di(2,4,6-trimethylphenyl)phosphino)-5-(2,6-diisopropylanilido)-2,7-di-tert-butyl-9,9-dimethylxanthene). The solid-state structure of (PON)Ga (obtained from X-ray crystallography) reveals very weak O…Ga and P…Ga interactions, consistent with a R2NGa fragment which closely resembles those found in one-coordinate amidogallium systems. Strong N-to-Ga pi donation from the amido substituent is reflected in a very short N-Ga distance (1.961(2) angstrom), while the P…Ga contact (3.076(1) angstrom) is well outside the sum of the respective covalent radii. While the donor properties of the PON ligand towards Ga-I are highly unsymmetrical, oxidation to Ga-III leads to much stronger coordination of the pendant phosphine as shown by P-Ga distances which are up to 20 % shorter. From a steric perspective, the PON ligand is shown to be significantly bulkier than related beta-diketiminate systems, a finding consistent with reactions of (PON)Ga towards O-atom sources that proceed without oligomerization. Despite this, the enhanced P-donor properties brought about by oxidation at gallium are not sufficient to quench the reactivity of the highly polar Ga-O unit. Instead, intramolecular benzylic C-H activation is observed across the Ga-O bond of a transient gallanone intermediate.
A reaction mechanism is the microscopic path by which reactants are transformed into products. Each step is an elementary reaction. In my other articles, you can also check out more blogs about 109425-51-6. Category: amides-buliding-blocks.
Reference:
Amide – Wikipedia,
,Amide – an overview | ScienceDirect Topics