Chemistry is the experimental science by definition. We want to make observations to prove hypothesis. For this purpose, we perform experiments in the lab. , Name: 2-Aminoacetophenone hydrochloride, 5468-37-1, Name is 2-Aminoacetophenone hydrochloride, molecular formula is C8H10ClNO, belongs to amides-buliding-blocks compound. In a document, author is Shin, Dong Hee, introduce the new discover.
The discovery and optimization of various of indane amides as mutant IDH1 inhibitors via structure-based rational design were reported. The optimal compounds demonstrated both potent inhibition in IDH1(R132H) enzymatic activity and 2HG production in IDH1 mutant HT1080 cell line, favorable PK properties and great selectivity against IDH1(wt) and IDH2(R140Q). (C) 2017 Elsevier Ltd. All rights reserved.
A reaction mechanism is the microscopic path by which reactants are transformed into products. Each step is an elementary reaction. In my other articles, you can also check out more blogs about 5468-37-1. Name: 2-Aminoacetophenone hydrochloride.
Reference:
Amide – Wikipedia,
,Amide – an overview | ScienceDirect Topics