Catalysts are substances that increase the reaction rate of a chemical reaction without being consumed in the process. 4316-74-9, Name is Sodium 2-(methylamino)ethanesulfonate, SMILES is [Na+].CNCCS([O-])(=O)=O, belongs to amides-buliding-blocks compound. In a document, author is Park, Sang Ho, introduce the new discover, Computed Properties of https://www.ambeed.com/products/4316-74-9.html.
The first synthesis of isoxazole-4-carboxylic acid derivatives by domino isoxazole-isoxazole isomerization is reported. Fe(II)-catalyzed isomerization of 4-acyl-5-methoxy-/5-aminoisoxazoles (dioxane, 105 degrees C) leads to the formation of isoxazole-4-carboxylic esters and amides in good yields. 4-Formyl-5-methoxyisoxazoles give methyl oxazole-4-carboxylates under the same reaction conditions. Fe(II)-catalyzed isomerization of 4-acyl-5-methoxyisoxazoles under milder conditions (MeCN, 50 degrees C) allows the preparation of transient 2-acyl-2-(methoxycarbonyl)-2H-azirines. The azirines isomerize quantitatively either into isoxazoles under catalytic conditions (dioxane, 105 degrees C) or into oxazoles under noncatalytic thermolysis (o-dichlorobenzene, 170 degrees C). The mechanism of the isomerization and dependence of the reaction routes on substituents at starting isoxazole core and reaction conditions are discussed on the basis of DFT calculations.
The proportionality constant is the rate constant for the particular unimolecular reaction. the reaction rate is directly proportional to the concentration of the reactant. I hope my blog about 4316-74-9 is helpful to your research. Computed Properties of https://www.ambeed.com/products/4316-74-9.html.
Reference:
Amide – Wikipedia,
,Amide – an overview | ScienceDirect Topics