Chemo-enzymatic cascade processes are invaluable due to their ability to rapidly construct high-value products from available feedstock chemicals in a one-pot relay manner. In an article, author is Zhao, Zhenguang, once mentioned the application of 2491-20-5, Name is H-Ala-OMe.HCl, molecular formula is C4H10ClNO2, molecular weight is 139.58, MDL number is MFCD00063663, category is amides-buliding-blocks. Now introduce a scientific discovery about this category, Formula: https://www.ambeed.com/products/2491-20-5.html.
We developed a multidimensional vibrational circular dichroism system with a positional coordinate, making it possible to move in both x- and y-directions using an automatic stage. Quantum cascade laser (QCL) was used as a light source to achieve high intensity and narrow focusing. The QCL emitted light in the wavenumber range of 1500-1740 cm(-1), which encompassed absorption bands assigned to the stretching vibrations of amides I and II. The operation of the instrument was analyzed for samples containing amide groups. An aqueous solution of Gly-L-Leu or GIy-D-Leu was measured under the background absorbance as high as 3.5 due to the water medium. The spectra were recorded by scanning at 1.0 cm(-1) steps. The time required for performing measurement at each wavenumber was less than 1 s. The mirror-image relation was maintained between the optical antipodes. A peak assigned to amide II appeared clearly at around 1580 cm(-1). In the case of KBr pellets containing the same compounds, peaks assigned to amide I and II were observed. For two-dimensional pattering, a KBr pellet comprising two domains of amino acids (or L-Ala and D-Ser) was investigated. The distribution of each component within the pellet was obtained under the two-dimensional alignment at the spatial interval of 2.5 mm.
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Reference:
Amide – Wikipedia,
,Amide – an overview | ScienceDirect Topics